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Description
Human IgG4 Fc , His tagProduct Specification Species Human Synonyms Ig gamma 4 chain C region, IGHG4 Accession P01861 Amino Acid Sequence Protein sequence(P01861, Glu99 Gly326, with C 10*His) ESKYGPPCPSCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGGGGGSHHHHHHHHHH Expression System HEK293 Molecular Weight
Product Specification
| Species | Human |
| Synonyms | Ig gamma-4 chain C region, IGHG4 |
| Accession | P01861 |
| Amino Acid Sequence | Protein sequence(P01861, Glu99-Gly326, with C-10*His) ESKYGPPCPSCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:27.3kDa Actual:33kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | with C-10*His |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. Fc binds to various cell receptors and complement proteins. In this way, it mediates different physiological effects of antibodies (detection of opsonized particles; cell lysis; degranulation of mast cells, basophils, and eosinophils; and other processes).
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4.9 ★★★★★
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Product Reviews
★★★★★ 3
Some errors
Format: Paperback
Not too good as I think. Some error between hard copy and online q&a bank. Very careful if you want to study with this
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Reviewed in the United States on August 21, 2025
★★★★★ 1
Poor quality, the book is already falling apart.
Format: Paperback
This is a review on quality of the book NOT the content.
I just got the book today and the binding on the cover came off immediately. It’s very poorly made!!!
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Reviewed in the United States on May 31, 2026
★★★★★ 1
Description is misleading
Format: Paperback
The description states that the book includes the access code. That is not true, the access code has been used and publisher is not honoring coffee
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Reviewed in the United States on April 24, 2026
★★★★★ 5
Book as advertised
Format: Paperback
Book as advertised
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Reviewed in the United States on March 7, 2026
★★★★★ 5
good quality
Format: Paperback
Good quality book. Bought for NP school.
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Reviewed in the United States on January 21, 2026
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