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Description
(PhS)2PD-NH2-C1-PEG3-Glutarate-MTzReferences: 1) Shao, S.; et al. Site specific and hydrophilic ADCs through disulfide bridged linker and branched PEG. Bioorg. Med. Chem. Lett. 2018, 28(8), 1363 1370. DOI: 10. 1016 j. bmcl. 2018. 03. 005 Keywords: Disulfide Rebridging; Chemical Conjugation; ADC; Thiol pyridazinedione 2) Fernndez, M.; et al. Fine tuning thio pyridazinediones as SMDC scaffolds (with intracellular thiol release via a novel self immolative linker). Chem. Commun. 2020, 56,
References:
1) Shao, S.; et al. Site-specific and hydrophilic ADCs through disulfide-bridged linker and branched PEG. Bioorg. Med. Chem. Lett. 2018, 28(8), 1363-1370.
DOI: 10.1016/j.bmcl.2018.03.005
Keywords: Disulfide Rebridging; Chemical Conjugation; ADC; Thiol-pyridazinedione
2) Fernández, M.; et al. Fine-tuning thio-pyridazinediones as SMDC scaffolds (with intracellular thiol release via a novel self-immolative linker). Chem. Commun. 2020, 56, 1125-1128.
DOI: 10.1039/C9CC08744C
Keywords: Disulfide Rebridging; Chemical Conjugation; SMDC; Thiol-pyridazinedione
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