Methylfolate - 5 mg, 60 Capsules
SKU: 19118235760

Methylfolate - 5 mg, 60 Capsules

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Description

Methylfolate - 5 mg, 60 CapsulesFolate is a vital B vitamin that plays a key role in methylationa critical process for DNA synthesis, detoxification, neurotransmitter production, and cardiovascular health. Our formula delivers 5 mg of Quatrefolic, the most advanced and bioavailable form of folate, designed to bypass genetic polymorphisms (such as MTHFR) that impair folic acid metabolism.* Why Quatrefolic? Quatrefolic is the glucosamine salt of (6S) 5 methyltetrahydrofolatethe

Folate is a vital B vitamin that plays a key role in methylation—a critical process for DNA synthesis, detoxification, neurotransmitter production, and cardiovascular health. Our formula delivers 5 mg of Quatrefolic®, the most advanced and bioavailable form of folate, designed to bypass genetic polymorphisms (such as MTHFR) that impair folic acid metabolism.*

Why Quatrefolic®?

Quatrefolic® is the glucosamine salt of (6S)-5-methyltetrahydrofolate—the bioactive form of folate that the body uses directly, without requiring conversion. Unlike folic acid, which must go through multiple enzymatic steps to become active, Quatrefolic® is ready for immediate uptake and use at the cellular level.*

  • Clinically studied for enhanced bioavailability
  • Supports methylation pathways*
  • Supports healthy homocysteine balance*
  • Supports mood and cardiovascular health*
  • Essential for fetal development and reproductive health*

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Who It's For

This high-dose formula is ideal for individuals with increased folate needs or those with MTHFR gene variants who may have trouble converting folic acid to its usable form.*

How It Works

Folate is required to convert homocysteine into methionine—a process vital for cardiovascular and neurological function. It also supports the production of neurotransmitters like serotonin, dopamine, and norepinephrine, which influence mood and cognition.*

What Makes Ours Better?

  • Longevity Focused: We leverage cutting-edge advancements in aging research to formulate products that address the fundamental causes of aging.*
  • Triple Lab Tested: Every product is tested three times by independent 3rd-party labs to ensure we meet the highest standards.
  • Complete Transparency: In an industry flooded with fake supplements, we stand apart by publishing our 3rd-party lab test results. We’re committed to showing you exactly what’s in every bottle, so you can feel confident in what you’re putting into your body. 
  • USA Manufacturing Excellence: Made in FDA-regulated, GMP-certified facilities in the USA for the highest quality and safety standards.
  • 100-Day Risk-Free Guarantee: We stand behind our products. Not satisfied? Reach out to our Santa Barbara, CA office for a full refund within 100 days – no hassle, no questions.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

References:

1 Bani Soheila, J Caring Sci 2013 
2 Mazza A. et al. Biol Regul Homeost Agents 2016
3 Rima Obeid R., Herrmann W. FEBS Letters 580, 2006
4 Stover Patrick, Curr Opin Biotechnol 2017
Seshadri S. at al. N Engl J Med 2002 
6 Bottiglieri T, J Neurol Neurosurg Psychiatry 2000 
7 Thaler C.J. 2014 
8 Stover PJ. Modern Nutrition in Health and Disease 2012
9 Tinelli C, Di Pino A Front. Nutr. 2019

Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
Folate (as Quatrefolic® (6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 8,500 mcg DFE** (5 mg) 2,125%
* Daily Value (DV) **DFE (Dietary Folate Equivalent) 
REV. 10.24 
  • OTHER INGREDIENTS: Vegetable cellulose (capsule), cellulose.
  • SUGGESTED DAILY USE: Take one (1) capsule daily, or as directed by your healthcare professional.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18 or are undergoing treatment for a
    medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
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SKU: 19118235760

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mysticelder
Battle Creek, US
★★★★★ 5
Gilbert conveys the principles of BFST in easily understood and engaging ways
Format: Paperback
Roberta Gilbert ' s book is simply transformative. Be forewarned, if you seriously apply Gilbert's principles from Bowen family systems theory your life will never be the same. Gilbert conveys the principles of BFST in easily understood and engaging ways. Your life and your relationships with others will become extraordinary as you become more emotional mature in your interactions with others. In short, an extraordinary book!
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Reviewed in the United States on January 5, 2015
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S Mancusi
Charlottesville, US
★★★★★ 3
A bit repetitive
Format: Paperback
The Family Systems approach makes a great deal of sense and is very helpful. But this book seems to be somewhat formulaic - every case looks the same.
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Reviewed in the United States on September 13, 2013
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Placeholder
San Leandro, US
★★★★★ 5
Extremely enlightening!
Format: Paperback
A psychologist recommended I read this book as my daughter and I were having issues. Wow! What you'll find in this book will change your whole thinking about relationships with family members. Very enlightening as to why we all behave as we do and what affect our behavior has on the development of our children. A MUST read for every parent. I bought a copy for each of our children and grandchildren to read.
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Reviewed in the United States on July 31, 2010
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Xandra
Carnegie, US
★★★★★ 4
Some good advice
Format: Paperback
Roberta Gilbert's "Extraordinary Relationships" offers useful advice for dealing with family relationships couched amidst an examination of systems theory. Although it is more technical than a lot of self help, it can be used by a general audience. Gilbert examines the theory of Murray Bowen, who countered notions of individual psychology (like those of Freud) with the theory that personality develops as a result of a family unit. The nuclear family, like a herd of amimals, reacts against each other, speaking a common language that is known only to them. Children raised in that family then detach from the family to form their own adult relationships, where dynamics may follow the family system. In order to heal adult problems, the author offers some practical advice, like taking the time to observe old patterns as they crop up (family Christmas fights come to mind) with the dispassionate mind of an observer. The author states that individuals will better be able to understand family dynamics and their role in them by doing this. I've read this book twice, and it has helped me better understand my family, and my role within it. I would recommend it for those who are seeking to better understand their family of origin, and what they can do to improve their present life through understanding the past.
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Reviewed in the United States on November 9, 2002
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Richard Davila
Omaha, US
★★★★★ 5
Good book
Format: Paperback
a very interesting book for the good reader.
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Reviewed in the United States on March 2, 2026

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