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Description
VEGF-C Recombinant Rabbit mAb (SDT-084-30)Product Specification Host Rabbit Antigen VEGF C Synonyms Vascular endothelial growth factor C, Flt4 L, VRP Immunogen Recombinant Protein Location N A Accession P49767 Clone Number SDT 084 30 Antibody Type Rabbit mAb Application Sandwich ELISA Reactivity Hu Cross Reactivity Does not recognize VEGF 121, VEGF 165 Purification Protein A Concentration 2 mg ml Purity >95% by HPLC Physical Appearance Liquid Storage Buffer PBS, pH 7. 4, 0. 03% Proclin 300
Product Specification
| Host | Rabbit |
| Antigen | VEGF-C |
| Synonyms | Vascular endothelial growth factor C, Flt4-L, VRP |
| Immunogen | Recombinant Protein |
| Location | N/A |
| Accession | P49767 |
| Clone Number | SDT-084-30 |
| Antibody Type | Rabbit mAb |
| Application | Sandwich ELISA |
| Reactivity | Hu |
| Cross Reactivity | Does not recognize VEGF-121, VEGF-165 |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Purity | >95% by HPLC |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, pH 7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Background
Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEGF) family. The main function of VEGF-C is to promote the growth of lymphatic vessels (lymphangiogenesis). It acts on lymphatic endothelial cells (LECs) primarily via its receptor VEGFR-3 promoting survival, growth and migration. In human tumour tissue samples VEGF-C was detected in some carcinomas in the low protein range. The ELISA will be a useful tool for investigations concerning the physiological function of VEGF-C in lymphangiogenesis under normal and pathophysiological conditions.
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