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Description
Stemulation Radiance Essentials - Save 10%Save 10% with Radiance Essentials from Stemulation. Experience an accelerated return to beautiful, healthy, younger looking skin. The Radiance Essentials Collection comprises a laser focused combining of Facial Serum, Boost Crme, AHA Toner, and Daily Micro Scrub, all by Stemulation. The collection is configured to defy gravity and resist the damaging effects of free radicals. It will tighten, brighten, and renew the vital glow of healthy skin cells
Save 10% with Radiance Essentials from Stemulation. Experience an accelerated return to beautiful, healthy, younger-looking skin. The Radiance Essentials Collection comprises a laser-focused combining of Facial Serum, Boost Crème, AHA Toner, and Daily Micro Scrub, all by Stemulation. The collection is configured to defy gravity and resist the damaging effects of free radicals. It will tighten, brighten, and renew the vital glow of healthy skin cells - and the result you'll see is tightened, brightened skin, and the renewed glow of vital, healthy skin cells, all resulting in beautiful and youthful skin. The results you'll see in the first 14 days will be dramatic.The Facial Serum is gentle enough to be used as an eye crème around the eyes.
Ingredients:
See "Ingredients" tab, at left.
Features
- Includes: Facial Serum 0.5 fl. oz., Boos Crème 0.5 fl. oz., AHA Toner 4 fl. oz., Daily Micro Derm Scrub 8 fl. oz.
- Accelerates your revival to beautiful, healthy, younger-looking skin.
- Free radicals' effects are resisted, and gravity is defied.
- You'll see dramatic results within the first 14 days after beginning use.
Ingredients
Radiance Essentials Ingredients
Facial Serum:
- Aloe Barbadensis (Aloe Vera) Leaf Juice
- HMSC Cultured Media (stem cell extract) Glycerin
- Dipeptide Diaminobutyroyl Benzylamide Diacetate
- Sodium Ascorbyl Phosphate
- Beta Glucan
- Dimethicone
- Vitus Vinifera (Grape) Seed Oil
- Myristoyl Pentapeptide-8
- Niacinamide
- Stearyl Alcohol
- Aribica Extract
- Tocopherol
- Ascorbyl Palmitate
- Camellia Sinensis (Green Tea) Leaf Extract
- Vitis Vinifera (Grape) Seed Extract
- Vaccinium Myrtillus (Bilberry) Extract
- Silybum Marianum (Milk Thistle) Extract
- Pinus Pinaster Bark (Maritime Pine) Extract
- Ginkgo Biloba Extract
- Curcuma longa (Turmeric) Root Extract
- Sodium Stearoyl Lactylate
- Glyceryl Stearate
- Hydroxyethylcellulose
- Xanthan Gum
- Disodium EDTA
- Fragrance (Parfum)
- Phenoxyethanol
- Ethylhexylglycerin.
Daily Micro Derm Scrub:
- Water (Aqua)
- Aloe Barbadensis (Organic Aloe Vera) Leaf Juice
- Diatomaceous Earth
- Sodium Lauroyl Methyl Isethionate
- Sodium Lauroyl Sarcosinate
- Glycerine
- Camellia Sinensis (Green Tea) Leaf Extract
- Vitis Vinifera (Grape) Seed Extract
- Vaccinium Myrtillus (Bilberry) Extract
- Silybum Marianum (Milk Thistle) Extract
- Pinus Pinaster Bark (Maritime Pine) Extract
- Ginkgo Biloba Extract
- Sodium Lactate
- Citrus Grandis (Grapefruit) Peel Oil
- Citrus Aurantium Dulcis (Orange) Peel Oil
- Na-Carbomer
- Xanthan Gum
- Potassium Sorbate
- Phenoxyethanol
- Ethylhexylglycerin
Boost Crème:
- Water
- Aloe Barbadensis (Aloe Vera) Leaf Juice
- Caprylic Capric Triglycerides
- Beta Glucan
- Lactic Acid
- Vitus Vinifera (Grape) Seed Oil
- Cyclopentasiloxane
- Dimethiconol
- Glyceryl Stearate
- PEG-100 Stearate
- Glycerin
- Myristoyl Pentapeptide-8
- Hydrolyzed Rice Bran Protein
- Oxido Reductases
- Glycine Soja (Soybean) Protein
- Niacinamide
- Methylsulfonylmethane
- Panthenol
- Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
- Abrica Extract
- Camellia Sinensis (Green Tea) Leaf Extract
- Vitis Vinifera (Grape) Seed Extract
- Vaccinium Myrtillus (Bilberry) Extract
- Silybum Marianum (Milk Thistle) Extract
- Pinus Pinaster Bark (Maritime Pine) Extract
- Ginkgo Biloba Extract
- Sodium Lactate
- Tocopherol
- Ascorbyl Palmitate
- Xanthan Gum
- Steareth-21
- Laureth-4
- Disodium EDTA
- Fragrance (Parfum)
- Phenoxyethanol
- Ethylhexylglycerin
- Potassium Sorbate
- Sodium Benzoate
AHA Balancing Toner:
- Water (Aqua)
- Aloe Barbadensis ( Aloe Vera) Leaf Juice
- Hamamelis Virginiana (Witch Hazel) Bark/Leaf/Twig Extract
- Lactic Acid
- Cucumis Sativus (Cucumber) Fruit Extract
- Sodium Lactate
- Camellia Sinensis (Green Tea) Leaf Extract
- Vitis Vinifera (Grape) Seed Extract
- Vaccinium Myrtillus (Bilberry) Extract
- Silybum Marianum (Milk Thistle) Extract
- Pinus Pinaster Bark (Maritime Pine) Extract
- Ginkgo Biloba Extract
- Citrus Grandis (Grapefruit) Peel Oil
- Cymbopogon Schoenanthus (Lemongrass) Oil
- Pentylene Glycol
- Guar Hydroxypropyltrimonium Chloride
- Isoceteth-20
- Potassium Sorbate
- Sodium Benzoate
- Phenoxyethanol
- Caramel
Using Stemulation Products
Using Stemulation® Products
Stemulation works for ALL skin types:
Stemulation works in reverse compared with most products on the market. Rather than the product dictating what the body needs, as do most products, Stemulation’s growth factors respond to the cells needs to help nurture and balance the health of the skin and tissue, thus addressing each individual need.
Ages 13 to 103 benefit:
Stemulation Luxury Skin Care offers exceptional quality ingredients designed to improve the overall health and vitality of the skin. Stemulation products contain numerous ingredients to slow the aging process. Nevertheless Stemulation has seen wonderful results with a variety of traditional troubled skin conditions and has made a tremendous impact on individuals as young as 13 suffering from breakouts by using the scrub, the serum and the boost. Since Stemulation has such an impact on the health and vitality of the skin, ages 13 to 103 will enjoy the improved texture, tone and healthy glow that Stemulation skin care produces. You can create or adjust your individual regimen will based on whether you are in the preventive or restorative stage in your skin care routine.
Use with other products?
YOU BETCHA!! Stemulation formulas are designed to augment and enhance a disciplined skin care routine. They do not interfere with ingredients in other products. Stemulation does recommended to apply its products first to cleansed skin and then proceed with your regular routine. For the best results, use Stemulation twice daily. If you use a retinol product or any glycolic, or lactic product is being used, it is not advisable to use the Boost Crème at the same time. The combination would be too aggressive and may cause irritation.
FAQ
Frequently Asked Questions
Is Stemulation safe?
Stemulation products have no known side effects. Neither we nor Stemulation give medical advice and if you are pregant or nursing, you should always consult your doctor for their medical opinion. However, the Stemulation medical advisory team and their research shows these products to bee non-invasive and safe to use while pregnant.
Why is Stemulation different?
Numerous skin care manufacturers use growth factors from a variety of sources. Stemulation, howoever, is the first product to use growth factors from the source, the stem cell itself. Like all things natural, fresh and new is usually better, and offers a higher degree of potency. Augmenting Stemulation's ground-breaking science, only the highest quality ingredients are used, producing products with exceptional efficacy providing users with a truly unique luxury skin care experience.
What can be expected, when beginning to use Stemulation products?
The mainstay of the Stemulation product line is the Boost Crème. It is the one product that you should not live without. You can add it to your existing regimen, or you can include it in developing a complete protocol. Using Stemulation Facial Serum, you'll notice a visible and tactile improvement to both the tone and texture of your skin. It will feel softer and smoother, and more vibrant and alive.
The Stemulation Boost Crème formulation opens pathways to allow the serum to penetrate more deeply into the dermis for more potent efficacy. Boost Crème will almost literally pull out impurities. When used as directed, the Boost Crème in combination with the Serum will tighten pores and improve skin texture within a week to 10 days. In the even you should experience any minor break out, continue with the products and the condition will improve in a few days, leaving beautiful results.
The Stemulation Boost Crème formulation opens pathways to allow the serum to penetrate more deeply into the dermis for more potent efficacy. Boost Crème will almost literally pull out impurities. When used as directed, the Boost Crème in combination with the Serum will tighten pores and improve skin texture within a week to 10 days. In the even you should experience any minor break out, continue with the products and the condition will improve in a few days, leaving beautiful results.
What about specific conditions?
Persons with rare skin conditions that include collagen over-production, or who are allergic to peptides, should avoid use.
Animal testing:
No Stemulation product is ever animal tested.
Does the scrub contain micro beads?
No. Stemulation used Diatomaceous Earth, which is a type of fossilized organic aquatic organisms, seaweek, and pumas. These ingredients are food grade, similar to toothpaste.
Is Stemulation organic?
Stemulation uses 85% to 87% organic and botanical ingredients. Some synthetic ingredients are used to enhance both stability and performance.
About Stem Cells
- Stemulation conditioned media was analyzed and tested at Stanford University for both its quality and its purity.
- The Stemulation advisory tem includes a renowned quadruple board certified cosmetic surgeon.
- Stemulation works with qualified pharmaceutical labs that have received GMP (good manufacturing practice) certifications.
- Stemulation new product development team includes two PhDs. &nbs;The original research work was conducted with UCI (University of California, Irvine) at the Bill and Susan Gross Stem Cell Research facility.
- Almost all Stemulation products use aloe as the base due to its anti-inflammatory properties and its ability to help promote healing.
- Stemulation is laser-focused on our their formulations with a goal of using as many botanical and natural ingredients as possible to enrich the products. The botanicals used are filled with nutrients and anti-oxidants that help support the effects of the stem cell science. Stemulation is real science with real results –– a true confluence of science and nature.
Stem Cells and Stemulation®:
Stem cells are used to produce growth factors, cytokines and proteins through a cell proliferation process to create the conditioned media used in Stemulation® formulas. Conditioned media is the fluid that contains the growth factors, cytokines and peptides once the stem cells are removed. Conditioned media is the active ingredient in Stemulation.
Growth factors, cytokines and peptides:
Put simply, growth factors are the "messenger signals" that tell body cells to respond. As the “EMT of the bodyâ€, Mesenchymal stem cells tend to be drawn to the location of a trauma and begin a cell proliferation process that produces cytokines (aka peptides), growth factors, and proteins that direct the body’s response from the nearby and surrounding cells. Stemulation® has enabled the same effect with the stem cells bypassed by utilizing the conditioned media that has been produced by the stem cells.
Stem Cell Origin:
Stemulation® uses only donor-certified stem cells sourced from GMP Medical Laboratories. The stem cells are derived from donated bone marrow and are non-embryonic. These stem cells are the are the identical quality and sources that supply cells for research and transplantation.
Types of Stem Cells:
Only Mesenchymal Stem Cells are used because they are pluripotent. Mesenchymal stem cells are from bone marrow but more specifically, pluripotent cells are cells that are capable of differentiating into one of many cell types such as skin, bone, tissue and blood.
Mesenchymal stem cells in the body:
These are the "medical signaling" cells of the body that act as the "emergency medical team" of they body. They function to direct the body's healthy cells to respond to any deficiency or trauma.
Stemulation® products CONTAIN NO STEM CELLS.
Stem cells are unable to live outside of a carefully controlled environment - such as the body or in the lab. Also, the molecular size of stem cells is too large to be absorbed by the skin. It's simply not possible, and any product claiming to contain actual stem cells is providing misinformation.
About Stemulation
Laurie Nicoll
Founder
Michelle Kleker
Executive Vice President
Prior to founding Stemulation, Laurie Nicoll's background included tenure at a stem cell research company. In 2008 she was inspired to harness the power and science of stem cells in a revolutionary way. She became driven to find a method by which to capture the healing properties of stem cells for use aesthetically. Additionally fueled by her personal skin challenges, Ms. Nicoll gathered a team of experts to accomplish her goal. The team comprised doctors and scientists each of whom specialized in the field of stem cell therapies, and from such renowned institutions as University of Southern California, Irvine’s well-known Bill and Susan Gross Stem Cell Research Center. After two years of research and development the culmination was the creation of Stemulation Skin Care.
The Stemulation management team as a combined business background of 50 years' management. The Stemulation Board of Directors comprises medical, aesthetic, retail, cosmetic industry professionals, and luxury resort executives. The Board brings in experience from leaders at world-renowned firms including Revlon, Dauphin, Guinot, Lancome, and Hyatt International.
Founder's Statement
"Stemulation Skin Care is committed to creating exceptional and ethically-produced skin care products. Giving back is central to our corporate culture. The Footprints Foundation was formed to leave a legacy, as our footprints in the sand remind us we can’t make it alone. Through The Footprints Foundation, Stemulation supports a variety of philanthropic organizations with a focus on empowering women and serving our community. Character defines you personally and professionally. We strive to always live life honestly, ethically and fearlessly with passion, tolerance, and compassion, above all else." - Laurie Nicoll
Some Important Points
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.4 ★★★★★
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Product Reviews
★★★★★ 1
Not as I expected
Color: Chew Pair, Size: Mini (Pack of 2)
The chew pair is so small. It looks more like it is for a hamster than for a small dog of almost any size. What a waste of money!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 24, 2026
★★★★★ 3
Not worth it
Color: Chew Pair, Size: Mini (Pack of 2)
My 3 month old Bernedoodle chewed up the string in about 5 min. But she really likes the barbell part and it’s held up well.
I’m not even going to give her the bone toy, after reading these reviews.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 19, 2020
★★★★★ 5
Nanner
Color: Chew Pair, Size: Mini (Pack of 2)
My fur baby loves her toys
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 23, 2026
★★★★★ 5
Must have dog toy!
Size: Extra Small, Style: Bristle Bone
I bought the PetSafe Busy Buddy Treat Ring Variety Pack for our 15 lb Shih Tzu and he absolutely LOVES it. The second he sees me pull it out, he gets so excited. We use it mostly to keep him entertained while we pull our cockatiels out of their cage for the day.
This is such a great toy for mental stimulation and keeping him busy. It’s interactive, keeps him focused, and makes treat time last longer instead of him just inhaling snacks in two seconds.
The rings are extremely durable, they treats fit really well, and it’s nice having a variety pack. It’s also a great option for small dogs who need enrichment without it being too heavy or difficult to use. The rings have no odd smell like other toys do. They come in an array of sizes and this particular one has little bristles that work as a tooth brush while he is using it as well.
Highly recommend if you’re looking for an enrichment toy, treat toy, or something to keep your dog entertained at home especially if you are using it for what we are.
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Reviewed in the United States on January 15, 2026
★★★★★ 5
The best safe, chew toy that offers variety and a challenge to keep your dog occupied.
Size: Medium, Style: Bristle Bone
My 60-lb, male Golden Retriever LOVES this bone. My first mistake was I put it together too tight; second mistake I loosened it too much and he had it pulled apart in no time. Now, it's just right. He wasn't sure about it, honestly, for about 5 hours. He is a chewer, he gets bored quickly, he's such a great dog I wanted him to have something indestructible, safe, and allow him different types of chewing in one toy. OH MY GOODNESS! This toy checks all the boxes. I did think I bought a Large; turned out to be a medium which is really perfect, for 50 to 90 lb dogs. And what came with this purchases was a bag of the treat rings. So glad I did! Finding the right chew toy to occupy this adorable boy has been a challenge. PetSafe, you met the challenge! Thank you so much!!
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Reviewed in the United States on October 24, 2025