PEA400
SKU: 86791399435

PEA400

Sale price$39.56 Regular price$43.95
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Ships within 48 hours · Estimated delivery Jul 9 - Jul 14

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Description

PEA400PEA (palmitoylethanolamide) is a fatty acid like compound naturally found in foods. Natural Factors PEA is naturally produced from fractionated non GMO safflower oil. It then undergoes a micronization process for improved solubility and absorption. PEA has been shown to be helpful in managing occasional pain and discomfort.* THE POWER OF PHYTORESPONSE! TM PhytoResponse refers to plant foods and herbs that can modulate and positively influence the

PEA (palmitoylethanolamide) is a fatty-acid-like compound naturally found in foods. Natural Factors PEA is naturally produced from fractionated non-GMO safflower oil. It then undergoes a micronization process for improved solubility and absorption. PEA has been shown to be helpful in managing occasional pain and discomfort.*

THE POWER OF PHYTORESPONSE!TM

PhytoResponse refers to plant foods and herbs that can modulate and positively influence the Endocannabinoid System (ECS) directly or indirectly and support the body’s production of endocannabinoids with non-cannabis, plant-based botanical compounds. The ECS promotes homeostasis, or balance.

THE POWER OF PEA AND THE ENDOCANNABINOID SYSTEM

PEA (N-palmitoylethanolamide) is an endogenous fatty acid amide that belongs to the family of biologically active lipids that are increased by the body to soothe discomfort. PEA is a member of the ECS with several biological functions, including neuromodulatory activity in the central nervous system. It has been demonstrated to be effective on the different inflammatory mechanisms that develop and maintain both neurogenic and neuropathic pain.

There are two sources of PEA commercially available. Synthetic forms require the use of powerful synthetic solvents. PEA can be naturally derived from safflower oil. PEA400 only utilizes naturally derived palmitoylethanolamide from safflower seed.

Natural Factors PEA400 is gluten free, third-party certified non-GMO, and suitable for vegetarians and vegans.

  • Helps manage occasional pain and discomfort*
Shipping Notes
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SKU: 86791399435

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4.6 ★★★★★
Based on 892 reviews
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Verified Purchase
Eden Reads Books
Grantham, US
★★★★★ 4
Sort of good for tough chewers??
Color: Deep Roots Carrot - Small, Size: Small Dog
The actual carrot part (orange part) is tough chewer approved and my dog loves. It’s basically the same shape and size as his kong. However the leaves (green part) is not tough chewer approved. He ripped ALL those leaves off and ate them within 5 minutes of me giving him the toy. However they passed through him fine.
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Reviewed in the United States on June 8, 2025
J
Verified Purchase
JessicaSB
Natrona Heights, US
★★★★★ 5
Aggressive chewer puppy approved
Color: Cinamutt Roll - Large, Size: Large
My aggressive chewer puppy loves this. It is pretty sturdy. He hasn't destroyed it yet and he's had it for over 3 months now.
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Reviewed in the United States on March 10, 2026
J
Verified Purchase
Jordan
Charlottesville, US
★★★★★ 1
Pieces off in minutes.
Color: Origin - Large, Size: Medium/Large Dog
My pup chewed pieces off in minutes.
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Reviewed in the United States on June 6, 2026
A
Verified Purchase
Amazon Customer
Birmingham, US
★★★★★ 3
Pretty hard to clean
Color: Cinamutt Roll - Large, Size: Large
We've had this for about a week now. I have 2 dogs, one small one about 55lb. I bought this for my big girl, but lil man is determined to get the best of this toy. Usually they don't both go after the same toys, so this is interesting. The trouble is, neither one of them can get all the treats out if something makes it all the way down into the crevice. It's surprisingly deep. The up side is that they'll try for quite a while before giving up. The down side is even if you put it in the top rack of the dishwasher, something stuck deep in there isn't going anywhere until you dig it out yourself. I tried a plastic knife but it broke the second time I used it in there. I wound up using the metal handle of a reusable straw cleaner. Which then I had to wash that, too. Then it needs to dry overnight before it can be used again. All in all, the dogs like it fine, it's gross to scrape out and wash, takes longer than most toys to dry, and I have the feeling that will eventually cause me to pass it to someone else's dog long before my two have gotten tired of it. At this point I'm pulling out of the toy rotation for a week or two because I'm not ready to clean it a third time.
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Reviewed in the United States on November 16, 2024
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Verified Purchase
Dogmom120
Battle Creek, US
★★★★★ 5
Hyena Proof
Color: Acorn - Large, Size: Large
I have an American Bulldog that would chew a brick if he didn’t have an alternative lying around. They won’t last forever (nothing does) but we’ve had two of these over the course of a year and for him that is nothing short of a miracle. And that is daily chewing like it’s his job. I highly recommend the Acornucopia for aggressive chewers with jaws like hyenas…so it’s probably great for your dog too.
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Reviewed in the United States on June 7, 2026

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