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Description
Advanced Clinicals Retinol Anti-Wrinkle Serum – Smooth, Firm & Renew (1.75oz)Reveal visibly smoother, firmer, and more radiant skin with the Advanced Clinicals Retinol Anti Wrinkle Serum. This lightweight, silky serum absorbs quickly to help refine texture and reduce the look of fine lines. Formulated with a renewing blend of Retinol, Squalane, Vitamin E, and Green Tea Extract, it nourishes the skin while supporting elasticity for a revitalized, youthful looking complexion. The gentle, milky formula glides on
Reveal visibly smoother, firmer, and more radiant skin with the Advanced Clinicals Retinol Anti-Wrinkle Serum. This lightweight, silky serum absorbs quickly to help refine texture and reduce the look of fine lines.
Formulated with a renewing blend of Retinol, Squalane, Vitamin E, and Green Tea Extract, it nourishes the skin while supporting elasticity for a revitalized, youthful-looking complexion. The gentle, milky formula glides on effortlessly—leaving skin soft, hydrated, and renewed without greasiness.
- Smooths the look of fine lines & wrinkles
- Supports visibly firmer, more refined skin
- Nourishes with Squalane & Vitamin E
- Antioxidant support from Green Tea
- Lightweight, milky texture layers well under moisturizer
- PM use: apply a thin layer to clean, dry face & neck.
- Introduce gradually (2–3x/week), then increase as tolerated.
- Use SPF daily; avoid pairing with direct acids in the same routine.
Retinol: A powerhouse ingredient that helps reduce the appearance of fine lines, wrinkles, and crepey looking skin, promoting a visibly smoother, firmer-looking complexion.
Squalane: Derived from sugar cane, lightweight emollient that helps lock in essential moisture and nourishes skin, keeping it soft & hydrated.
Green Tea Extract: Rich in antioxidants, smooths and refreshes dull looking skin while softening the appearance of fine lines and wrinkles.
Vitamin E: Antioxidant that nourishes for softer, smoother looking skin.
Disclaimer: We strive to maintain accurate ingredient information; however, ingredient lists may change due to innovative updates and evolving regulatory guidelines. For the most current details, please refer to the ingredient list on the product packaging.
Aqua/Water/Eau, Isopropyl Myristate, Glycerin, Ethylhexyl Olivate, Cetearyl Alcohol, Pyrus Malus (Apple) Fruit Extract, Squalane, Aloe Barbadensis Leaf Juice Powder, Propanediol, Avena Sativa (Oat) Bran Extract, Retinol, Tocopherol, Camellia Sinensis Leaf Extract, Oryza Sativa (Rice) Bran Extract, Citrus Aurantium Dulcis (Orange) Peel Extract, Helianthus Annuus (Sunflower) Extract, Humulus Lupulus (Hops) Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Helianthus Annuus (Sunflower) Seed Oil, Ammonium Acryloyldimethyltaurate/VP Copolymer, Phenoxyethanol, Caprylyl Glycol Ethylhexylglycerin, Hexylene Glycol, Cyamopsis Tetragonoloba (Guar) Gum, Copernicia Cerifera (Carnauba) Wax, Polysorbate 20, Tetrasodium Glutamate Diacetate, 1,2-Hexanediol, Disodium Cocoamphodipropionate, Xanthan Gum, Ethyl Ferulate, Parfum/Fragrance, Limonene.
- Paraben-free & cruelty-free
- Dermatologist-tested
- Suitable for most skin types
- Size: 1.75oz / 52ml
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Exchange/Return Notes
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4.2 ★★★★★
Based on 397 reviews
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Product Reviews
★★★★★ 5
PERFECT!
Size: 19 Ounce (Pack of 1)
My favorite daily face cream, thick but absorbs fast, fights wrinkles, non-oily, discreet fresh scent, and lasts forever!
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Reviewed in the United States on June 6, 2026
★★★★★ 5
Gentle but effective
Size: 4 Fl Oz
I’ve used quite a few exfoliating products over the years, but I keep coming back to this one because blackheads seem determined to make themselves at home in my pores. No matter how consistent I am with the rest of my skincare routine, they always find a way to show up, especially around my nose and chin.
What I like most about this exfoliant is that it works without feeling harsh. It has a lightweight liquid texture that applies easily and absorbs quickly. Unlike physical scrubs that can leave my skin feeling irritated or over-exfoliated, this provides gentle chemical exfoliation with none of the rough scrubbing. My skin feels smoother after use, and I don’t get the tight, stripped feeling that some acne-focused products can cause.
After using it regularly, I notice fewer clogged pores and a visible reduction in blackheads. My pores also look less noticeable, and my skin texture appears more even overall. It helps keep congestion under control before it turns into larger blemishes, which is a big reason why it has remained a staple in my routine.
For me, this is one of those rare products that manages to be both effective and gentle at the same time. If blackheads and clogged pores are an ongoing battle, this has been one of the most reliable products I’ve found for keeping them under control while still being comfortable enough for regular use.
Summary: This exfoliant has earned a permanent spot in my skincare routine. It helps reduce blackheads, keeps my pores looking clearer, and improves overall skin texture without irritating my skin. For anyone dealing with persistent pore congestion, it’s easy to see why this product has such a loyal following.
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Reviewed in the United States on June 4, 2026
★★★★★ 5
If you actually understand how to use it, it's amazing.
Size: 4 Fl Oz
My skin type:
- Very Dry, easily dehydrated
- Oily nose
- Prone to stubborn acne and closed comedones
- Redness on chin and cheeks (not rosacea)
I already use a nightly Tretinoin cream (.04% concentration) to help with my acne and premature signs of aging but decided with my derm that incorporating a BHA would be a good idea to help with my seriously stubborn closed comedones and some irritating textural issues. It was between this and the Cerave SA lotion and I ultimately decided on this due to the higher concentration of salicylic acid.
It's moisturizing, and feels sticky for the first 5-10 minutes after application but seems to sinks in to something of a satin finish on me and I can no longer feel it on my skin. You just have to be a little patient. My skin feels well hydrated and plump after it settles and looks really smooth and my pores aren't as obvious. It sits just fine under makeup for me but I'm not a new user to chemical exfoliants so I don't have lots of dead skin pilling up or sloughing off when I use it, my skin is, for the most part, already very smooth outside the acne and CCs. Occasionally I'll apply it further down my neck/decolletage than usual and WOW do I old skin just ball up and peel right away - it's so gross but also satisfying. So those that don't exfoliate often or are new to BHA/AHAs will likely have issues with foundation until their skin adjusts (but it will adjust). My advice in those cases is to either use this at night for the first few weeks or just accept going barefaced for a little while if you can.
I'd strongly suggest not applying this product over anything that you feel does not dry down fully, the times I've attempted to use it after serums or heavier products it takes forever to sink in and sometimes never fully does. I save all my serums and essences for after this has absorbed and it's far easier to work with it as a result. My steps go like this most days: ACWell Licorice toner --- PC 2% BHA --- 10% Niacinamide serum --- TO Matryxil serum --- Secret Key Black Snail cream or Syn-ake cream w/ 3 drops Stratia Fortify oil --- Sunscreen.
It works fairly quickly IMO, on my neck where I typically don't apply my Tret at night I noticed the peeling and balling of dead skin on day one and on my face where I have a patch of really awful CCs I noticed them getting smaller and smoother by around day 3-4. I'm going on about 8 days now and they're barely visible unless I'm right up in the mirror and feel as if they're almost gone when I touch my fingers to that area. I do have some slight peeling of the skin around my mouth and nose but it's not terrible (likely because I already exfoliate the heck out of my skin with the tret).
Some tips and things keep in mind:
1)
DO NOT RINSE IT OFF. I don't understand some of the top reviews advising people to do that, it says on the bottle not to rinse and nearly all chemical exfoliators are meant to be left on until the next cleansing specifically so they can do their job. If you rinse it off you're either going to prevent it from properly exfoliating or end up irritating the hell out of your skin. If you have oily skin and feel this might be heavy on you than you can probably just use this on bare skin and then sunscreen if you use in the AM or a lightweight lotion/cream and be done with it, but you need to leave it on your skin.
2)
You have got to use sunscreen while you're using this product! Any BHA or AHA exfoliant causes increased sun sensitivity and you have to address that in your routine. You should already use sunscreen daily but it becomes a must when you incorporate a chemical exfoliator or you risk sun damage.
3)
Less is more! Don't slop this on your face or soak a cotton pad in it, a little goes a long way and you'll be kicking yourself if you apply way too much and have to wait 20+ minutes for it to sink in. Use a shake or two and add more if needed but go easy.
4)
Expect some irritation initially. Chemical exfoliants can be harsh and rough even on sturdy skin and you have to give yourself time to adjust. Over-exfoliation is a possibility but sometimes just introducing a BHA or AHA into your routine can cause some sensitivity. Don't panic and just be gentle to your skin. Use ceramides (like Cerave Skin Renewing cream) or fatty oils to soothe your face if needed and try to stay away from any harsh products or acids like Vitamin C right after applying this to avoid really burning your face.
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Reviewed in the United States on January 9, 2020
★★★★★ 5
Amazing exfoliating toner
Size: 4 Fl Oz
I am almost 40 and have had acne since puberty. I have tried so many products. The products that showed some improvement (like Proactiv) changed the texture of my face. Literally made my face feel like a basketball. I’ve tried some products that I’ll notice an improvement after a week or so, and the it would just stop working. I have never used something that so drastically helped my face in such a short amount of time. Notably, within 5 days my blemishes were almost gone. Within a week, my chin felt smooth instead of feeling the bumps of every clogged pore. The discoloration of my face, such as the redness, hasn’t totally disappeared, but it is improving. My face doesn’t feel oily throughout the day. My skin feels tighter, like I got a facelift. Moisturizer along with this product is important. And it is important to follow the directions and start slowly with this product. Use it every other day for the first week, gradually working your way up to daily and then twice a day. It is a shock to your skin and can dry it out if you go overboard. But for what I needed this product for, it has exceeded my expectations in every way. I couldn’t recommend it more. Just a heads up, it is applied like a toner. I expected a face wash, but it is a liquid that you apply to cotton and rub on your face. I wash with CeraVe SA cleanser, follow it with this, and apply whatever moisturizer you prefer—I’ve been using moisturizer with SPF so as to not damage my skin more than I already have.
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Reviewed in the United States on May 12, 2026
★★★★★ 4
PRODUCT WORKS GREAT IF USED CONSISTENLTY!
Size: 4 Fl Oz
Paula's Choice Liquid Exfoliant does exactly what it states. After applying the liquid product to my face with a cotton pad, it deeply cleansed the pores and exfoliated the top layer of dead skin cells without the harsh granular feel of most other exfoliants. It is important to continue using it regularly for the best results because, initially, the exfoliated skin was dry and flaky. Using a washcloth helped remove the flaky skin, followed by a moisturizer. After continued use, there was no more flaky skin. It was replaced with a smoother, more evenly toned skin tone.
REMEBER TO USE A LOT OF SUNSCREEN AND TO REAPPLY IT THROUGHOUT THE DAY!
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Reviewed in the United States on April 19, 2026